File:Coccidioides-Endospores-and-Spherules-Draw-Strong-Chemotactic-Adhesive-and-Phagocytic-Responses-by-pone.0129522.s002.ogv
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Coccidioides-Endospores-and-Spherules-Draw-Strong-Chemotactic-Adhesive-and-Phagocytic-Responses-by-pone.0129522.s002.ogv (Ogg Theora video file, length 44 s, 400 × 320 pixels, 260 kbps, file size: 1.36 MB)
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[edit]DescriptionCoccidioides-Endospores-and-Spherules-Draw-Strong-Chemotactic-Adhesive-and-Phagocytic-Responses-by-pone.0129522.s002.ogv |
English: Phagocytosis of C . posadasii endospores by human neutrophils. This video combines 3 movies of phagocytosis experiments in which a C. posadasii endospore was brought into contact with a pipette-held neutrophil and released (in the presence of heat-treated, autologous serum). Brief cell-target contact sufficed to establish adhesion and initiate phagocytosis. At the onset of target uptake, all neutrophils formed a protrusive "pedestal" that at first displaced the endospore outwards (i.e., away from the main cell body), which we have identified as a distinctive, target-specific morphological feature of neutrophil interaction with fungal particles (in heat-treated serum). (All 3 videos are sped up about 90 times.) |
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Source | S2 Video from Lee C, Thompson III G, Hastey C, Hodge G, Lunetta J, Pappagianis D, Heinrich V (2015). "Coccidioides Endospores and Spherules Draw Strong Chemotactic, Adhesive, and Phagocytic Responses by Individual Human Neutrophils". PLOS ONE. DOI:10.1371/journal.pone.0129522. PMID 26070210. PMC: 4466529. | ||
Author | Lee C, Thompson III G, Hastey C, Hodge G, Lunetta J, Pappagianis D, Heinrich V | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 12:24, 24 June 2015 | 44 s, 400 × 320 (1.36 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Phagocytosis of C . posadasii endospores by human neutrophils. |
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Author | Lee C, Thompson III G, Hastey C, Hodge G, Lunetta J, Pappagianis D, Heinrich V |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | This video combines 3 movies of phagocytosis experiments in which a C. posadasii endospore was brought into contact with a pipette-held neutrophil and released (in the presence of heat-treated, autologous serum). Brief cell-target contact sufficed to establish adhesion and initiate phagocytosis. At the onset of target uptake, all neutrophils formed a protrusive "pedestal" that at first displaced the endospore outwards (i.e., away from the main cell body), which we have identified as a distinctive, target-specific morphological feature of neutrophil interaction with fungal particles (in heat-treated serum). (All 3 videos are sped up about 90 times.) |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2015-06-12 |