File:Chemotaxis-in-Densely-Populated-Tissue-Determines-Germinal-Center-Anatomy-and-Cell-Motility-A-New-pone.0027650.s009.ogv

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Chemotaxis-in-Densely-Populated-Tissue-Determines-Germinal-Center-Anatomy-and-Cell-Motility-A-New-pone.0027650.s009.ogv(Ogg Theora video file, length 25 s, 324 × 424 pixels, 3.24 Mbps, file size: 9.68 MB)

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English: Primary follicle homeostasis. The video begins with an empty BTU. As time progresses, lymphocytes enter the tissue. Colors: naive B-cells (red) and naive CD4/8. Driven by chemotaxis, naive B-cells migrate to the FDC populated follicle in response to CXCL13, while memory B-cells and T-cells remain in the FRC populated extrafollicular region in response to CCL21/19. Cells remain in the BTU for ∼12–24 hours, at which point they change their chemotaxis preference to the exit chemokine S1P and actively leave via efferent lymphatics at the bottom of the tissue (exiting naive B-cells shown in yellow).
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Source Video S2 from Hawkins J, Jones M, Plassmann P, Thorley-Lawson D (2011). "Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues". PLOS ONE. DOI:10.1371/journal.pone.0027650. PMID 22145018. PMC: 3228727.
Author Hawkins J, Jones M, Plassmann P, Thorley-Lawson D
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
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Date/TimeThumbnailDimensionsUserComment
current03:55, 14 November 201225 s, 324 × 424 (9.68 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 360P 583 kbps Completed 18:50, 21 August 2018 42 s
Streaming 360p (VP9) 584 kbps Completed 03:02, 31 January 2024 1.0 s
VP9 240P 289 kbps Completed 18:49, 21 August 2018 24 s
Streaming 240p (VP9) 290 kbps Completed 05:42, 6 December 2023 1.0 s
WebM 360P 474 kbps Completed 07:05, 16 November 2012 57 s
Streaming 144p (MJPEG) 1.14 Mbps Completed 02:45, 2 November 2023 1.0 s

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