File:Calcium-sensing-receptors-signal-constitutive-macropinocytosis-and-facilitate-the-uptake-of-NOD2-ncomms11284-s6.ogv

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Calcium-sensing-receptors-signal-constitutive-macropinocytosis-and-facilitate-the-uptake-of-NOD2-ncomms11284-s6.ogv ‎(Ogg Theora video file, length 5.7 s, 496 × 255 pixels, 249 kbps, file size: 174 KB)

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English: Supplementary Movie 5 PtdIns(3,4,5)P3 levels are reduced at the plasma membrane and in the membrane ruffles upon CaSR inhibition. hMDMs were transfected with the PtdIns(3,4,5)P3 probe (PH)Akt-GFP and imaged live by spinning disc confocal microscopy in calcium-containing medium, acquiring images every 15 sec for 10 min. NPS2143 (10 μM) was added to the cells immediately prior to initiating image acquisition. Membrane ruffles retract and the (PH)Akt-GFP probe is lost from the plasma membrane. The video is displayed at 7 frames per sec.
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Source Video file from Canton J, Schlam D, Breuer C, Gütschow M, Glogauer M, Grinstein S (2016). "Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages". Nature Communications. DOI:10.1038/ncomms11284. PMID 27050483. PMC: 4823870.
Author Canton J, Schlam D, Breuer C, Gütschow M, Glogauer M, Grinstein S
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This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
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Date/TimeThumbnailDimensionsUserComment
current10:16, 28 October 20165.7 s, 496 × 255 (174 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 240P 82 kbps Completed 00:33, 21 August 2018 2.0 s
Streaming 240p (VP9) 82 kbps Completed 05:26, 5 December 2023 1.0 s
WebM 360P 104 kbps Completed 23:41, 29 November 2023 1.0 s
Streaming 144p (MJPEG) 163 kbps Completed 17:38, 1 November 2023 1.0 s

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