File:Aurora-A-drives-early-signalling-and-vesicle-dynamics-during-T-cell-activation-ncomms11389-s11.ogv
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[edit]DescriptionAurora-A-drives-early-signalling-and-vesicle-dynamics-during-T-cell-activation-ncomms11389-s11.ogv |
English: Supplementary Movie 10 4D imaging of Actin ring formation in conjugates of in control and Aurora A-inhibited Jurkat cells. Control Jurkat T cells transfected with mCherry-β-actin were pre-treated with MLN8237 or vehicle, allowed to settle on stimulatory anti-CD3/CD28-coated surfaces and recorded under a confocal microscope. Fluorescence and bright field images for XYZ-stacks were taken every 25 s. MLN8237 or vehicle was present in the imaging medium. Bar, 10 μm. Movie was mounted at 10 fps. |
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Source | Video file from Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces N, Sánchez-Madrid F (2016). "Aurora A drives early signalling and vesicle dynamics during T-cell activation". Nature Communications. DOI:10.1038/ncomms11389. PMID 27091106. PMC: 4838898. | ||
Author | Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces N, Sánchez-Madrid F | ||
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![]() ![]() This file is licensed under the Creative Commons Attribution 4.0 International license.
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current | 06:22, 28 October 2016 | 1.9 s, 858 × 332 (296 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Supplementary Movie 10 |
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Author | Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces N, Sánchez-Madrid F |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | 4D imaging of Actin ring formation in conjugates of in control and Aurora A-inhibited Jurkat cells. Control Jurkat T cells transfected with mCherry-β-actin were pre-treated with MLN8237 or vehicle, allowed to settle on stimulatory anti-CD3/CD28-coated surfaces and recorded under a confocal microscope. Fluorescence and bright field images for XYZ-stacks were taken every 25 s. MLN8237 or vehicle was present in the imaging medium. Bar, 10 μm. Movie was mounted at 10 fps. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2016-04-19 |
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19 April 2016
application/ogg
9b00c68cb96954469097acfbbcd3a7a7409fa2ae
302,635 byte
1.9 second
332 pixel
858 pixel
Categories:
- CD antigens
- CD3 antigens
- T-lymphocyte differentiation antigens
- Aurora kinase A
- Cytoplasmic vesicles
- Gene expression regulation
- Immunological synapses
- Interleukin-2 receptor alpha subunit
- C-type lectins
- Lymphocyte activation
- Lymphocyte specific protein tyrosine kinase p56
- Transgenic mice
- Protein kinase inhibitors
- T-cell antigen receptors
- Videos of signal transduction