File:Adult-Onset-Niemann–Pick-Disease-Type-C-Rapid-Treatment-Initiation-Advised-but-Early-Diagnosis-Video 1.ogv
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[edit]DescriptionAdult-Onset-Niemann–Pick-Disease-Type-C-Rapid-Treatment-Initiation-Advised-but-Early-Diagnosis-Video 1.ogv |
English: Illustration of motor symptoms in two adolescent/adult-onset NP-C patients. 00:00: patient 1, approximately 15 years after onset of motor symptoms. 00:05: demonstration of supranuclear, predominantly vertical gaze palsy. Inhibition of horizontal saccade initiation and pursuit movements should also be noted. 00:35: upper limb ataxia. 00:51: lower limb ataxia. 01:09: gait ataxia; disabling limb dystonia is obvious. 01:35: NP-C patient 2. 01:40: vertical gaze palsy. 01:56: positive applause sign. 02:08: gait ataxia. 02:13: postural reflexes. |
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Source | Video S1 from Piroth T, Boelmans K, Amtage F, Rijntjes M, Wierciochin A, Musacchio T, Weiller C, Volkmann J, Klebe S (2017). "Adult-Onset Niemann–Pick Disease Type C: Rapid Treatment Initiation Advised but Early Diagnosis Remains Difficult". Frontiers in Neurology. DOI:10.3389/fneur.2017.00108. PMID 28421028. PMC: 5378773. | ||
Author | Piroth T, Boelmans K, Amtage F, Rijntjes M, Wierciochin A, Musacchio T, Weiller C, Volkmann J, Klebe S | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 21:08, 20 May 2017 | 2 min 25 s, 960 × 540 (28.89 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Piroth T, Boelmans K, Amtage F, Rijntjes M, Wierciochin A, Musacchio T, Weiller C, Volkmann J, Klebe S |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Illustration of motor symptoms in two adolescent/adult-onset NP-C patients. 00:00: patient 1, approximately 15 years after onset of motor symptoms. 00:05: demonstration of supranuclear, predominantly vertical gaze palsy. Inhibition of horizontal saccade initiation and pursuit movements should also be noted. 00:35: upper limb ataxia. 00:51: lower limb ataxia. 01:09: gait ataxia; disabling limb dystonia is obvious. 01:35: NP-C patient 2. 01:40: vertical gaze palsy. 01:56: positive applause sign. 02:08: gait ataxia. 02:13: postural reflexes. |
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Language | English |