File:Actomyosin-dependent-dynamic-spatial-patterns-of-cytoskeletal-components-drive-mesoscale-podosome-ncomms13127-s22.ogv

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English: Supplementary Movie 21 Animation depicting the dynamic spatial patterns. Individual podosomes continuously undergo growth (dark red cones) and shrinkage (light red cones) cycles due to actin polymerization. Within a cluster, podosome neighbours are connected by myosin decorated actin filaments (red arrows) that drive a spatial coordination of actin and force oscillations resulting in a wave-like phenomenon. These continuous actin waves directly drive the recruitment of vinculin (green) and talin (blue) resulting in mesoscale dynamic spatial patterns within the cluster that extend well beyond the nearest neighbour. For simplicity, the actin filaments connecting individual podosomes to the cell membrane are not depicted.
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Source Video file from Meddens M, Pandzic E, Slotman J, Guillet D, Joosten B, Mennens S, Paardekooper L, Houtsmuller A, van den Dries K, Wiseman P, Cambi A (2016). "Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization". Nature Communications. DOI:10.1038/ncomms13127. PMID 27721497. PMC: 5062568.
Author Meddens M, Pandzic E, Slotman J, Guillet D, Joosten B, Mennens S, Paardekooper L, Houtsmuller A, van den Dries K, Wiseman P, Cambi A
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Date/TimeThumbnailDimensionsUserComment
current16:41, 29 October 201630 s, 1,024 × 589 (1.09 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 94 kbps Completed 18:22, 16 August 2018 5.0 s
Streaming 480p (VP9) 94 kbps Completed 13:54, 17 December 2023 1.0 s
VP9 360P 55 kbps Completed 18:22, 16 August 2018 4.0 s
Streaming 360p (VP9) 55 kbps Completed 13:14, 27 December 2023 2.0 s
VP9 240P 30 kbps Completed 18:22, 16 August 2018 3.0 s
Streaming 240p (VP9) 30 kbps Completed 15:13, 9 December 2023 1.0 s
WebM 360P 256 kbps Completed 16:41, 29 October 2016 3.0 s
Streaming 144p (MJPEG) 97 kbps Completed 19:18, 29 October 2023 1.0 s

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