File:A-RIAMlamellipodin–talin–integrin-complex-forms-the-tip-of-sticky-fingers-that-guide-cell-migration-ncomms9492-s13.ogv
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A-RIAMlamellipodin–talin–integrin-complex-forms-the-tip-of-sticky-fingers-that-guide-cell-migration-ncomms9492-s13.ogv (Ogg Theora video file, length 6.4 s, 358 × 358 pixels, 706 kbps, file size: 552 KB)
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English: Supplementary Movie 12 The MIT complex drives lamellipodial protrusion. NIH-3T3 cells expressing the membrane marker mCherry-K-Ras-Caax and either control shRNA (CT) or RIAM shRNA (KD) were transiently transfected with constructs encoding BFP-RIAM(WT), talin-binding defective BFP-RIAM(4E) mutant or BFP alone. Cells were plated on fibrinogen for 2 h and imaged by spinning disk confocal microscopy (SDCM) at 5 sec interval for 3 min. Scale bar: 5 μm. |
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| Source | Video file from Lagarrigue F, Vikas Anekal P, Lee H, Bachir A, Ablack J, Horwitz A, Ginsberg M (2015). "A RIAM/lamellipodin–talin–integrin complex forms the tip of sticky fingers that guide cell migration". Nature Communications. DOI:10.1038/ncomms9492. PMID 26419705. PMC: 4589889. | ||
| Author | Lagarrigue F, Vikas Anekal P, Lee H, Bachir A, Ablack J, Horwitz A, Ginsberg M | ||
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  This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 23:29, 30 October 2016 | 6.4 s, 358 × 358 (552 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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