File:A-Novel-Striated-Muscle-Specific-Myosin-Blocking-Drug-for-the-Study-of-Neuromuscular-Physiology-Video3.ogv
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[edit]DescriptionA-Novel-Striated-Muscle-Specific-Myosin-Blocking-Drug-for-the-Study-of-Neuromuscular-Physiology-Video3.ogv |
English: Development of fatigue in response to high-frequency nerve stimulation (HFS) in embryonic WT and Vamp2 mutant diaphragm. Thirty-second fluorescence videos of tonic phrenic nerve stimulation of the left side of E15.5 diaphragm at 1, 5, 10, and 20 Hz in WT (top panels) and Vamp2 mutant (bottom panels) mice. Note the failure in WT diaphragm to maintain peak shortening in response to 20 Hz stimulation. Note also the failure of Vamp2 mutant diaphragm to maintain the response to even 1 hz stimulation. |
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Source | Video 3 from Heredia D, Schubert D, Maligireddy S, Hennig G, Gould T (2016). "A Novel Striated Muscle-Specific Myosin-Blocking Drug for the Study of Neuromuscular Physiology". Frontiers in Cellular Neuroscience. DOI:10.3389/fncel.2016.00276. PMID 27990107. PMC: 5130989. | ||
Author | Heredia D, Schubert D, Maligireddy S, Hennig G, Gould T | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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current | 12:08, 1 February 2017 | 33 s, 1,280 × 564 (2.63 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Heredia D, Schubert D, Maligireddy S, Hennig G, Gould T |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Development of fatigue in response to high-frequency nerve stimulation (HFS) in embryonic WT and Vamp2 mutant diaphragm. Thirty-second fluorescence videos of tonic phrenic nerve stimulation of the left side of E15.5 diaphragm at 1, 5, 10, and 20 Hz in WT (top panels) and Vamp2 mutant (bottom panels) mice. Note the failure in WT diaphragm to maintain peak shortening in response to 20 Hz stimulation. Note also the failure of Vamp2 mutant diaphragm to maintain the response to even 1 hz stimulation. |
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Language | English |