File:Universal clocks for transformed age across mammals.webp

English: "The figure displays relative age estimates of universal clock 2 (clock 2) and log–linear-transformed age of universal clock 3 (clock 3). Relative age estimates incorporate maximum lifespan and assume values between 0 and 1. Log–linear age is formulated with ASM and gestational time. a–i, Age estimated by LOFO cross-validation for clock 2 and clock 3. j–l, Age estimated via LOSO cross-validation for clock 2. The DNAm estimates of age (y axes) of a–c are transformations of relative age (clock 2) or log–linear age (clock 3) into units of years. b,e, Only marsupials (nine species). Each panel reports a Pearson correlation (Cor) coefficient. The gray and black dashed lines correspond to the diagonal line (y=x) and the regression line, respectively. Median correlation (med.Cor) and median of MAE (med.MAE) are calculated across species (a–f) or across species–tissue (g–l). All correlation P values are highly significant (P < 1.0 × 10−22). Each sample is labeled by mammalian species index and indicated by tissue color (Supplementary Data 1.3–1.4). All P values reported are unadjusted and two sided."