File:Transformation of cells by exposure to initiator and promoter compounds.jpg

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English: reating healthy skin cells with only initiators or only promoters does not change the growth phenotype. Treating with an initiator followed by multiple treatments with promoters on an adjacent spot leads to no change. Treating with an initiator then multiple treatments with promoters at the same location (same cells) over time leads to papilloma formation. Over time without further treatment, the papilloma regresses. Treating as in the previous case with long-term promoter treatment maintains the papilloma. Treating as before and then exposing the papilloma to iniators causes carcinoma formation (i.e. a second genetic hit unleashes more agressive growth).
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Author WassermanLab

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current00:18, 4 March 2017Thumbnail for version as of 00:18, 4 March 2017800 × 1,068 (195 KB)WassermanLab (talk | contribs)User created page with UploadWizard

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