File:The Tiny, Circumspect Rival of the Central Nervous System.jpg
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Captions
Captions
Beta-amyloid plaque being covered by microglia and astrocytes in Alzheimer's brain
Summary[edit]
| Description |
English: Slight forgetfulness, typically categorised as absurd. Out-of-place answers, classically blamed on age. Perhaps this is familiar to you, as this is the reality of countless elderly people in our society. Alzheimer's disease, silent and cautious, wears down the brains of those who suffer from it. These carelessnesses are no longer sporadic, absences, bad manners or lack of initiative appear, and can even end in total disability. Is it not complex to think that one of its causes is the accumulation of an element even smaller than the COVID-19 virus? This image shows microglia and astrocytes, components of our brain's immune system, in the heat of battle against those beta-amyloid protein plaques, the drivers of the concatenation of events presented above. Being able to study them at this level of detail will allow us to better understand the pathology and, hopefully in the near future, to develop effective therapies against the origin of the disease.
Image taken with reflection confocal and/or scanning spectral fluorescence microscope LEICA Stellaris 8. Objective: HCX PL APO 63x/1.30 Glyc W.D. 0.30 mm. Composite made from 43 Z-planes with LASX 3D software and post-processed with FIJI.
Español: Olvidos leves, típicamente catalogados como absurdos. Contestaciones fuera de lugar, achacadas clásicamente a la edad. Quizás les suene, pues esta es la realidad de infinidad de mayores de nuestra sociedad. La Enfermedad de Alzheimer, silente y cautelosa, va desgastando el cerebro de quienes la padecen. Esos descuidos dejan de ser esporádicos, aparecen las ausencias, los malos modos o la falta de iniciativa, pudiendo terminar incluso en una total invalidez. ¿No les resulta complejo pensar que una de sus causas sea la acumulación de un elemento aún más pequeño que el virus del COVID-19? En esta imagen puede apreciarse a la microglía y los astrocitos, componentes de nuestro sistema inmune cerebral, en el fragor de la batalla contra esas placas de proteína beta amiloide, conductoras de la concatenación de hechos anteriormente presentados. El poder estudiarlos a este nivel de detalle nos permitirá una mejor comprensión de la patología y, esperemos en un futuro cercano, el desarrollo de terapias efectivas contra el origen de la enfermedad.
Imagen tomada con microscopio confocal de reflexión y/o de fluorescencia espectral de barrido LEICA Stellaris 8. Objetivo: HCX PL APO 63x/1.30 Glyc W.D. 0.30 mm. Composición hecha a partir de 43 planos en Z con software LASX 3D y procesada posteriormente con FIJI. English: Slight forgetfulness, typically categorised as absurd. Out-of-place answers, classically blamed on age. Perhaps this is familiar to you, as this is the reality of countless elderly people in our society. Alzheimer's disease, silent and cautious, wears down the brains of those who suffer from it. These carelessnesses are no longer sporadic, absences, bad manners or lack of initiative appear, and can even end in total disability. Is it not complex to think that one of its causes is the accumulation of an element even smaller than the COVID-19 virus? This image shows microglia and astrocytes, components of our brain's immune system, in the heat of battle against those beta-amyloid protein plaques, the drivers of the concatenation of events presented above. Being able to study them at this level of detail will allow us to better understand the pathology and, hopefully in the near future, to develop effective therapies against the origin of the disease. |
| Date | |
| Source | Own work |
| Author | Nicocapelo |
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This file was uploaded as part of Wiki Science Competition 2023. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 11:55, 29 November 2023 | | 3,293 × 1,842 (1.68 MB) | Nicocapelo (talk | contribs) | Uploaded own work with UploadWizard |
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