File:Single-Cell-Analysis-of-Drug-Distribution-by-Intravital-Imaging-pone.0060988.g006.jpg

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English: The segmentation algorithm was combined with a linking program to determine individual cell nuclear drug concentrations. A. The locations of cell nuclei were tracked over 5 hours, using external linking software in a video where both cell movement and image drift were present. Red boxes indicate arbitrarily selected cells used for manual tracking verification of the algorithm. B. Manual tracking of arbitrarily selected cells. C. By combining results using the segmentation algorithm together with the tracking data, drug concentration over time in 10 sample cells could be plotted.
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Source Image file from Giedt R, Koch P, Weissleder R (2013). "Single Cell Analysis of Drug Distribution by Intravital Imaging". PLOS ONE. DOI:10.1371/journal.pone.0060988. PMID 23593370. PMC: 3622689.
Author Giedt R, Koch P, Weissleder R
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current06:56, 8 May 2016Thumbnail for version as of 06:56, 8 May 2016683 × 606 (93 KB)Recitation-bot (talk | contribs)Automatic upload of media from: doi:10.1371/journal.pone.0060988

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