File:Overview of diverse HCMV proteome involved in modulation of host cell controlled growth.jpg

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日本語: UL76 ウイルス蛋白は、染色体の変異（chromosomal aberrations）を誘導する。

IE1 ウイルス蛋白は、テロメラーゼ活性（telomerase activity）を上げる。

IE1・IE2・pUL36・pUL37・pUL38 ウイルス蛋白は、アポトーシスを阻害するウイルス蛋白（anti-apoptotic proteins）で、腫瘍細胞の不死化を亢進させる。

IE1・pUL16・pUL18・pUS11・pp65・pp71 ウイルス蛋白は、免疫機構からの逃避（immune escape）に関わり、腫瘍免疫への抵抗性を上げる。

IE1・IE2・US28 ウイルス蛋白は、癌遺伝子として働くと推察される蛋白（putative oncogenes）。

IE1・IE2・US28・pUL97・pp65 ウイルス蛋白は、癌抑制遺伝子のカウンター蛋白質（viral counter proteins against tumor suppresors）であり、発癌の抑制を阻害する。
Date
Source Herbein G, Kumar A (2014). "The oncogenic potential of human cytomegalovirus and breast cancer". Frontiers of Oncology. 4: 230. PMCID: PMC4142708. PMID: 25202681. doi: 10.3389/fonc.2014.00230.
Author Georges Herbein, Amit Kumar

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