File:Osteoclasts obtained from monocyte.jpg
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Captions
Captions
Osteoclasts obtained from peripheral blood monocyte differentiation
Summary[edit]
| Description |
English: The giants of bone tissue: osteoclasts. Osteoclasts are specialized cells of bone tissue, originating from the fusion of multiple monocytes. The following image was captured using the optical microscope at 40x magnification. Osteoclasts were generated by treating peripheral blood monocytes with RANK-L proteins and MCSF, in Petri dishes with conditioned medium, for 21 days. In the boxes above you can observe the "brush border" of the cell, which allows the cell to anchor itself to the substrate, and the nuclei with the nucleoli grouped in the center, resulting from the fusion of the monocytes. In the bottom left box we can observe the formation of a new osteoclast, with the nuclei converging towards the center of the cell. The larger cell has created a channel through which the nuclei of another cell can flow to the center.
Italiano: I "giganti" dei tessuti ossei: gli osteoclasti. Gli osteoclasti sono cellule specializzate del tessuto osseo, originate dalla fusione di più monociti. L'immagine seguente è stata catturata utilizzando il microscopio ottico con ingrandimento 40x. Gli osteoclasti sono stati generati trattando i monociti del sangue periferico con proteine RANK-L e MCSF, in piastre Petri con terreno condizionato, per 21 giorni. Nei riquadri in alto si può osservare il “bordo a pennello” della cellula, che permette alla cellula di ancorarsi al substrato, e i nuclei con i nucleoli raggruppati al centro, risultanti dalla fusione dei monociti. Nel riquadro in basso a sinistra possiamo osservare la formazione di un nuovo osteoclasto, con i nuclei che convergono verso il centro della cellula. La cellula più grande ha creato un canale attraverso il quale i nuclei di un altra cellula possono fluire verso al centro. |
| Date | |
| Source | Own work |
| Author | Chitotriosidase |
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| current | 15:38, 18 December 2023 | | 3,255 × 2,421 (17.66 MB) | Chitotriosidase (talk | contribs) | Uploaded own work with UploadWizard |
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