File:Noninvasive cortisol biomarker monitoring using a wearable aptamer-field-effect transistor sensing system.jpg
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Summary[edit]
| Description |
English: "(A) The hypothalamus-pituitary-adrenal (HPA) axis controls cortisol levels in response to circadian rhythm and stress. ACTH, adrenocorticotropic hormone; CRH, corticotropin-releasing hormone. (B) The fraction of circulating cortisol not bound to blood plasma proteins is available for excretion by salivary and sweat glands. (C) Saliva and sweat samples can be analyzed by an aptamer-field-effect transistor (FET) sensing system. Top: Photograph of an aptamer-FET-enabled biosensing smartwatch. Bottom: Schematic illustration of cortisol sensing by an aptamer-FET sensor. VG, gate voltage; VS, source voltage; VD, drain voltage; ADC, analog-digital converter. (D) Photograph of a FET sensor array with In2O3 semiconductor channels fabricated on a flexible polyimide substrate. Schematic layers not to scale. (E) Expanded view of the key components of an aptamer-FET biosensing smartwatch. Liquid crystal display (LCD). (F) Overview of FET-array signal acquisition via a multichannel on-board source measurement unit (SMU). Data processing is via a microcontroller unit (MCU), display, and transmission. IDS, source-drain current; VGS, gate voltage. Photo credit: Zhaoqing Wang, Yichao Zhao, UCLA." |
| Date | |
| Source | https://www.science.org/doi/10.1126/sciadv.abk0967 |
| Author |
Authors of the study: Bo Wang https://orcid.org/0000-0002-3986-3415 Chuanzhen Zhao https://orcid.org/0000-0003-0162-1231 Zhaoqing Wang https://orcid.org/0000-0002-5548-3965 Kyung-Ae Yang https://orcid.org/0000-0001-5575-4107 Xuanbing Cheng https://orcid.org/0000-0001-7682-0759 Wenfei Liu https://orcid.org/0000-0003-1338-7905 Wenzhuo Yu https://orcid.org/0000-0002-1904-9088 Shuyu Lin https://orcid.org/0000-0002-5248-6124 Yichao Zhao https://orcid.org/0000-0002-2884-8105 Kevin M. Cheung https://orcid.org/0000-0003-1586-0364 Haisong Lin https://orcid.org/0000-0002-5684-6385 Hannaneh Hojaiji https://orcid.org/0000-0002-1963-5458 Paul S. Weiss https://orcid.org/0000-0001-5527-6248 Milan N. Stojanović https://orcid.org/0000-0001-6340-0982 A. Janet Tomiyama https://orcid.org/0000-0002-2152-5813 Anne M. Andrews https://orcid.org/0000-0002-1961-4833 and Sam Emaminejad |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 12:14, 2 September 2022 | | 3,900 × 2,974 (1.2 MB) | Prototyperspective (talk | contribs) | Uploaded a work by Authors of the study: Bo Wang https://orcid.org/0000-0002-3986-3415 Chuanzhen Zhao https://orcid.org/0000-0003-0162-1231 Zhaoqing Wang https://orcid.org/0000-0002-5548-3965 Kyung-Ae Yang https://orcid.org/0000-0001-5575-4107 Xuanbing Cheng https://orcid.org/0000-0001-7682-0759 Wenfei Liu https://orcid.org/0000-0003-1338-7905 Wenzhuo Yu https://orcid.org/0000-0002-1904-9088 Shuyu Lin https://orcid.org/0000-0002-5248-6124 Yichao Zhao https://orcid.org/0000-0002-2884-8105 Kevi... |
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