File:Metabolisme.png

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Metabolisme.png ‎(577 × 347 pixels, file size: 67 KB, MIME type: image/png)

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metabolisme

Summary[edit]

Description
English: Gambar 2. Jalur metabolisme utama PA. Ada empat jalur metabolisme utama: untuk PA, sebagai berikut: (I) dehidrogenasi, (II) hidrolisis, (III) N-oksidasi, dan (IV) N-glukuronidasi. Di antara mereka, dehidrogenasi PA diakui sebagai yang paling jalur aktivasi metabolik penting karena DHPA diproduksi oleh dehidrogenasi sangat elektrofilik dan dapat bergabung dengan makromolekul seluler penting seperti: protein dan asam nukleat untuk memulai toksisitas. Singkatan: CYP450, cytochrome P450; DHPA, alkaloid dehydropyrrolizidine; FMO, monooksigenase yang mengandung flavin; GSH, glutathione; PA, alkaloid pirolizidin; UGT, uridin difosfat glucuronosyltransferase.
Date
Source Own work
Author Citraazizah

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current16:18, 2 July 2021Thumbnail for version as of 16:18, 2 July 2021577 × 347 (67 KB)Citraazizah (talk | contribs)Uploaded own work with UploadWizard

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