File:Levodopa Wege.svg

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Deutsch: Aktivierung und Deaktivierung von Levodopa, mit Fokus auf die Mechanismen verschiedener Antiparkinson-Medikamente. COMT = Catecholamin-O-Methyltransferase, AADC = Aromatische-L-Aminosäure-Decarboxylase (DOPA-Decarboxylase), ZNS = zentrales Nervensystem, MAO-B = Monoaminoxidase B, DOPAC = 3,4-Dihydroxyphenylessigsäure ("Acetat").
3-Methoxytyrosin und DOPAC sind inaktiv, Dopamin in der Peripherie verursacht Nebenwirkungen aber keine Anti-Parkinson-Wirkung, und Dopamin im ZNS ist für die Anti-Parkinson-Wirkung verantwortlich.
Quelle: Mutschler, E; M Schäfer-Korting (2001) (in German) Arzneimittelwirkungen (8th ed.), Stuttgart: Wissenschaftliche Verlagsgesellschaft, pp. 313–316 ISBN: 3-8047-1763-2.
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Other versions File:Levodopa pathway.svg (English version)
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current20:25, 11 April 2017Thumbnail for version as of 20:25, 11 April 20171,041 × 1,043 (41 KB)Anypodetos (talk | contribs){{Information |Description ={{de|1=Aktivierung und Deaktivierung von Levodopa. COMT = Catecholamin-''O''-Methyltransferase, AADC = Aromatische-<small>L</small>-Aminosäure-Decarboxylase (DOPA-Decarboxylase), ZNS = zentrales Nervensystem, MAO-B = Mon...

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