File:Immune cell populations and the effects of immunosenescence on cellular function.jpg
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Italiano: Genetic regulatory mechanisms affected by immunosenescence. Regulation of cellular function is often mediated by changes at the genetic level. Covalent modifications on histone tails modulate the accessibility of DNA for transcription, methylation of CpG sequences in promoter regions can affect transcription factor binding, and miRNA expression can modulate gene silencing through a number of different mechanisms at the post-transcriptional level. All of these have been shown to be differentially regulated to some capacity with aging and associated with changes in immune cell function. |
| Date | |
| Source | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849399/ |
| Author | Stephen N. Crooke, Inna G. Ovsyannikova, Richard B. Kennedy, and Gregory A. Poland; Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN 55905 USA |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 12:36, 13 June 2021 | | 800 × 393 (218 KB) | OppidumNissenae (talk | contribs) | era un ritaglio |
| 12:33, 13 June 2021 |  | 256 × 246 (6 KB) | OppidumNissenae (talk | contribs) | Uploaded own work with UploadWizard |
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