File:HLA-DQ protein.PNG
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HLA-DQ_protein.PNG (420 × 424 pixels, file size: 15 KB, MIME type: image/png)
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DescriptionHLA-DQ protein.PNG |
English: Image shows how 4 isoforms can be produced as a result of 2 different haplotypes. DQ genes are expressed within the nucleus, the resulting RNA are transported out of the nucleus and independently translated into polypeptides and transported across the endoplasmic reticulum where alpha and beta chains are process and fold into their final form, a DQ heterodimer. While some alpha may prefer to pair with certain beta, in many instances they can pair to an isoform encoded by the other 'parents' haplotype resulting in a trans-isoform. When the isoforms are encoded by the same haplotype, the form a cis-haplotype isoform. |
Date | |
Source | Own work |
Author | Pdeitiker |
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Public domainPublic domainfalsefalse |
I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law. |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 19:26, 13 July 2008 | 420 × 424 (15 KB) | Pdeitiker (talk | contribs) | {{Information |Description={{en|1=Image shows how 4 isoforms ''can'' be produced as a result of 2 different haplotypes. DQ genes are expressed within the nucleus, the resulting RNA are transported out of the nucleus and independently translated into polyp |
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