File:General pathology; from the 11th rev. German ed. (1921) (14578244140).jpg

Identifier: cu31924104226240 (find matches)
Title: General pathology; from the 11th rev. German ed.
Year: 1921 (1920s)
Authors: Ziegler, Ernst, 1849-1905 Symmers, Douglas, ed
Subjects: Pathology
Publisher: New York, Wood
Contributing Library: Cornell University Library
Digitizing Sponsor: MSN

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dule in the left groin and another on the left fore-arm. In this patient, leprosy bacilli occurred in the nasal secretions in great profusion. 502 THE PATHOGENIC FISSION-FUNGI. § 174. The Bacillus mallei was discovered by Loffler, Schiitz, andIsrael in glanders foci, and later confirmed and studied by Weichselbaum,Kitt, and others. It is the cause of glanders (malleus, maliasmus) and offarcy (skin glanders, malleus farciminosus), a contagious disease ofhorses, which occurs in man chiefly through transmission from horses. The glanders bacilli are small, slender rods, which occur in thediseased foci, sometimes scattered, sometimes lying in small clumps.Alkaline methylene-blue or gentian-violet is employed for their staining.The bacilli at times appear in the blood (Loffler, Kitt). The bacilli grow at a temperature of 30°-40° C, on coagulated blood-serum, potato, and agar. On blood-serum they form small yellowishtransparent drops which later become milky white. On agar the colonies W^
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Fig. 45S.—Glanders of a cats testicle (Mullets fluid, hEematoxylin), a, Seminiferous tubules;b, c, tubules filled with leucocytes; d, foci of leucocytes in the cennective tissue. X go. are grayish-white. In cultures club-shaped forms and threads are notinfrequently seen. Spore-formation has not been demonstrated. Horses, asses, sheep, young dogs, goats, cats, guinea-pigs, and field-mice are suitable for inoculation. In cats, after inoculation, there developin the testicles cellular foci consisting of leucocytes (Fig. 458), whichlie in the canaliculi (h, c) and around them (d). The injection of thepus of glanders into the peritoneal cavity of male guinea-pigs causes thetesticles to swell rapidly (Straus). This reaction is of great diagnosticvalue. After subcutaneous inoculation ulcers develop at the seat ofinoculation, followed by swelling of the neighboring lymph-nodes. Later,nodules may develop in the internal organs, and ulcers may be formedin the nose. Typical glanders may be pro

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