File:GE23077-binds-to-the-RNA-polymerase-i-and-i+1-sites-and-prevents-the-binding-of-initiating-elife02450fs003.jpg
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DescriptionGE23077-binds-to-the-RNA-polymerase-i-and-i+1-sites-and-prevents-the-binding-of-initiating-elife02450fs003.jpg |
English: Sequence alignments for the β subunits of bacterial RNAP (top twenty-one sequences) and corresponding subunits of human RNAP I, RNAP II, and RNAP III (bottom three sequences), showing locations of GER substitutions in E. coli (black rectangles; sequences from Figure 2A) and S. pyogenes (black and gray rectangles; sequences in Supplementary file 2C). Species are as follows: E. coli (ECOLI), Haemophilus influenzae (HAEIN), Vibrio cholerae (VIBCH), Pseudomonas aeruginosa (PSEAE), Treponema pallidum (TREPA), Borrelia burgdorferi (BORBU), Xylella fastidiosa (XYLFA), Campylobacter jejuni (CAMJE), Neisseria meningitidis (NEIMA), Rickettsia prowazekii (RICPR), Chlamydia trachomatis (CHLTR), Mycoplasma pneumoniae (MYCPN), Bacillus subtilis (BACSU), Staphylococcus aureus (STAAU), Streptococcus pyogenes (STRP1), Mycobacterium tuberculosis (MYCTU), Synechocystis sp. PCC 6803 (SYNY3), Aquifex aeolicus (AQUAE), Deinococcus radiodurans (DEIRA), Thermus thermophilus (THETH), Thermus aquaticus (THEAQ), and Homo sapiens (HUMAN). |
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Source | Image file from Zhang Y, Degen D, Ho M, Sineva E, Ebright K, Ebright Y, Mekler V, Vahedian-Movahed H, Feng Y, Yin R, Tuske S, Irschik H, Jansen R, Maffioli S, Donadio S, Arnold E, Ebright R (2014). "GE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides". eLife. DOI:10.7554/eLife.02450. PMID 24755292. PMC: 3994528. | |
Author | Zhang Y, Degen D, Ho M, Sineva E, Ebright K, Ebright Y, Mekler V, Vahedian-Movahed H, Feng Y, Yin R, Tuske S, Irschik H, Jansen R, Maffioli S, Donadio S, Arnold E, Ebright R | |
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This file is licensed under the Creative Commons Attribution 3.0 Unported license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 12:10, 30 July 2014 | 722 × 876 (257 KB) | Recitation-bot (talk | contribs) | Automatic upload of media from: doi:10.7554/eLife.02450 |
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Horizontal resolution | 600 dpi |
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Number of components | 3 |
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Software used | Adobe Photoshop CS4 Windows |
Date and time of digitizing | 21:39, 3 April 2014 |
File change date and time | 13:20, 5 April 2014 |
Date metadata was last modified | 13:20, 5 April 2014 |
Unique ID of original document | xmp.did:03846CFE67BCE311B974E0B278369CE4 |