File:Fitness effects of an ftsZ mutation on populations of Mycoplasma mycoides.webp
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From the study "Evolution of a minimal cell"
Summary[edit]
| Description |
English: "We reengineered the nonsense mutation ftsZ E315* and quantified its effect on relative fitness in both the non-minimal and minimal cells using head-to-head competition assays. The ftsZ E315* nonsense mutation had a significant effect on Mycoplasma cell size that depended on cell type (two-way ANOVA, F1,32 = 7.45, P = 0.010). Compared to the wild type (non-evolved ancestor), the mutation increased relative fitness by 25% in the non-minimal cell and 14% in the minimal cell. Dark-coloured symbols represent the mean ± SEM. Light-coloured symbols represent values for each replicate population. Samples sizes are as follows: wild-type minimal cell, n = 12; ftsZ E315* minimal, n = 12; wild-type non-minimal cell, n = 5; ftsZ E315* non-minimal, n = 5.
Source Data" |
| Date | |
| Source | https://www.nature.com/articles/s41586-023-06288-x |
| Author | Authors of the study: R. Z. Moger-Reischer, J. I. Glass, K. S. Wise, L. Sun, D. M. C. Bittencourt, B. K. Lehmkuhl, D. R. Schoolmaster Jr, M. Lynch & J. T. Lennon |
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| current | 15:12, 7 September 2023 | | 1,000 × 1,087 (27 KB) | Prototyperspective (talk | contribs) | Uploaded a work by Authors of the study: R. Z. Moger-Reischer, J. I. Glass, K. S. Wise, L. Sun, D. M. C. Bittencourt, B. K. Lehmkuhl, D. R. Schoolmaster Jr, M. Lynch & J. T. Lennon from https://www.nature.com/articles/s41586-023-06288-x with UploadWizard |
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