File:DNA demethylation and histone demethylation regulate MET process during reprogramming.jpg

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Description Figure 4. DNA demethylation and histone demethylation regulate MET process during reprogramming. TET and TDG are essential for early MET through demethylating miR-200 loci and TET1 plays different roles in reprogramming in condition of the present or absent of vitamin C. Passive DNA demethylation through knockdown the expression of Dnmt1 also promote MET. Histone demethylases also regulate MET process in different ways.
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Source https://www.frontiersin.org/articles/10.3389/fcell.2020.00760/full Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming Front. Cell Dev. Biol., 06 August 2020 Sec. Molecular and Cellular Oncology Volume 8 - 2020 https://doi.org/10.3389/fcell.2020.00760
Author Lai Xiaowei, Li Qian, Wu Fang, Lin Jiechun, Chen Jiekai, Zheng Hui, Guo Lin
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Copyright © 2020 Lai, Li, Wu, Lin, Chen, Zheng and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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current19:12, 15 May 2024Thumbnail for version as of 19:12, 15 May 20242,968 × 992 (172 KB)Rasbak (talk | contribs){{Information |description=Figure 4. DNA demethylation and histone demethylation regulate MET process during reprogramming. TET and TDG are essential for early MET through demethylating miR-200 loci and TET1 plays different roles in reprogramming in condition of the present or absent of vitamin C. Passive DNA demethylation through knockdown the expression of Dnmt1 also promote MET. Histone demethylases also regulate MET process in different ways. |date=2020-08-06 |source=https://www.frontiers...

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