File:Conversion of 5-methylcytosine to 5-hydroxymetnylcytosine by TET enzyme plus alpha-ketoglutarate & Fe(II).jpg
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[edit]DescriptionConversion of 5-methylcytosine to 5-hydroxymetnylcytosine by TET enzyme plus alpha-ketoglutarate & Fe(II).jpg |
English: TET enzymes are dioxygenases in the family of alpha-ketoglutarate-dependent hydroxylases. A TET enzyme is an alpha-ketoglutarate (α-KG) dependent dioxygenase that catalyses an oxidation reaction by incorporating a single oxygen atom from molecular oxygen (O2) into its substrate, 5-methylcytosine (5mC). This conversion is coupled with the oxidation of the cosubstrate α-KG into succinate and carbon dioxide. |
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Source | Own work |
Author | Bernstein0275 |
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current | 00:43, 10 June 2020 | 2,036 × 1,620 (167 KB) | Bernstein0275 (talk | contribs) | Uploaded own work with UploadWizard |
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