File:Changes in various immune cell subsets during immunosenescence.jpg
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DescriptionChanges in various immune cell subsets during immunosenescence.jpg |
Italiano: Changes in various immune cell subsets during immunosenescence. Many immune cell subpopulations are altered during immunosenescence. Number of both naive T and B cells is decreased, but the number of memory T and B cells is increased. In the aging process, the diversity of TCR decreases with age. In addition, antigen recognition and presentation capabilities are reduced. In addition, the antigen presentation and phagocytosis ability of DC cells are reduced. NK cell function is reduced. The number and function of MDSCs and macrophages are increased |
Date | |
Source | Lian, Jingyao (2020-11-10). "Immunosenescence: a key player in cancer development". Journal of hematology & oncology 13 (1). Springer Science and Business Media LLC. DOI:10.1186/s13045-020-00986-z. PMID 33168037. PMC: 7653700. ISSN 1756-8722. |
Author |
Jingyao Lian 1 2, Ying Yue 1 2 3, Weina Yu 1 2, Yi Zhang 4 5 1-Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. 2-State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, 450052, Henan, China. 3-Clinical Laboratory, Henan Medical College Hospital Workers, Zhengzhou, 450000, Henan, China. 4-Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. yizhang@zzu.edu.cn. 5-State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, 450052, Henan, China. yizhang@zzu.edu.cn. |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 14:54, 14 June 2021 | 796 × 739 (109 KB) | OppidumNissenae (talk | contribs) | Uploaded a work by Jingyao Lian 1 2, Ying Yue 1 2 3, Weina Yu 1 2, Yi Zhang 4 5 1-Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. 2-State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou, 450052, Henan, China. 3-Clinical Laboratory, Henan Medical College Hospital Workers, Zhengzhou, 450000, Henan, China. 4-Biotherapy Center and Cancer Center, The First Affiliated Hospital... |
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