File:Bugs-Split-to-Attack-and-Gamble-to-Survive-pbio.1001929.g001.jpg

English: Bugs in tubes. A 13-hour time-lapse montage of images from the microfluidics device used for this study. The bottom of each tube is closed so that as bugs divide they move up the tube and are shed at the top. The blue bar in the middle indicates normal medium, the yellow bar indicates the use of depleted medium to induce the choice between T+ and T− phenotype, and the red bar indicates the challenge with the antibiotic ciprofloxacin. In the top row of images, the cell at the bottom of the tube has a T+ phenotype, as indicated by the green fluorescent protein reporter, and survives the antibiotic. In the bottom row, the corresponding cell is T− and perishes.