File:American journal of physiology (1898) (14781988822).jpg

Identifier: americanjourn01ameruoft (find matches)
Title: American journal of physiology
Year: 1898 (1890s)
Authors: American Physiological Society (1887- ) American Physiological Society (1887- ). Abstracts of papers presented at the fall meeting American Physiological Society (1887- ). Proceedings
Subjects: Physiology Physiology
Publisher: (Bethesda, Md., etc.) American Physiological Society (etc.)
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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llbelow it. The Cardiac Nerves in the Guinea-Pig. 387 At about the season when it was first noticed that excitation of thevagus was bringing the heart to a standstill, it was also noticed thatthe guinea-pigs under experiment did not live as long as they hadformerly done. Later it was noticed that they died very easily, andwithout any apparent cause ; no sooner were the necessary dissectionsmade, and the artery connected with the manometer, than the animaldied. Although the anaesthetics were used with great care, and variousones were tried, there was no improvement. At the season in ques-tion the dissection was done more carefully and more rapidly thanduring October, and everything pertaining to the operation was morefavorable than during the earlier months ; still the animals died beforeany results of value could be obtained. In many cases the tissues ofthe neck showed an unduly venous condition of the blood before thecannula was inserted into the artery; respiration ceased; the heart
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Figure 2. Four-fifths the original size. Inhibition from stimulation of the left vaguswith the secondary coil at 16 cm. Time in seconds. The line of zero pressure is notshown. The writing-points of the manometer and of the stimulating key were in thesame vertical line. became feeble, and the animal died. The heart usually continued tobeat for a short time after respiration had ceased ; artificial respira-tion, however, did not prolong the Ufe of the animal. In April itbecame practically impossible to get any results whatever from theexperiments. In order to be certain that the trouble was not whollywith the special lot of animals on hand, or with the hygienic condi-tions to which they were exposed, a new lot of animals was procured,but the results were not improved except in a few cases. The onlypossible explanation of these results seems to be that the lack ofvitality was due either to some unknown cause associated with theseason of the year, or to the diminution of fresh air and lig

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