File:American journal of physiology (1898) (14596576008).jpg

Identifier: americanjourna04ameruoft (find matches)
Title: American journal of physiology
Year: 1898 (1890s)
Authors: American Physiological Society (1887- ) American Physiological Society (1887- ). Abstracts of papers presented at the fall meeting American Physiological Society (1887- ). Proceedings
Subjects: Physiology Physiology
Publisher: (Bethesda, Md., etc.) American Physiological Society (etc.)
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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100 120 /40^. Figure 16. — The influence of load;the relative heights of the con-tractions, with loads of 20, 40, 60,SO, 100,120 and 140 grams. Drumturned by hand. Mammalian Smooth Muscle. — The Cafs Bladder. 205 The Duration of Irritability ; Fatigue. Sertoli,^ keeping his preparations for the greater part of the timeat a low temperature, has found that the erector penis muscle mayremain irritable for five, six, or even seven days. Various other ob-servers^ have noted the extreme slowness with which smooth muscledies under ordinary conditions. With the bladder muscle of the catthe duration of irritability at room temperatures is often as much astwenty-four to forty-eight hours, while one preparation, kept in anice-box at 5-8° C, responded to the faradic current at the end offour days. The bladder /;/ situ, with the circulation intact, does not, in thecourse of any ordinary series of experiments, show any evidence offatigue for very long periods. It does, however, show temporary
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Figure 17. — Fatigue curve. Contractions numbered 2-17, 29-41, 55-63, 92-100,121-128, and 149-154. Time intervals 10 seconds. Four-fifths the original size. fatigue if strong stimuli be repeated rapidly, as in producing tetanus,Even then recovery takes place within a short interval, the timevarying with the extent of the stimulation, and the experiments maybe proceeded with as before. It is impossible to completely reducethe contractility of a fresh muscle even under the most powerfulstimulation. With the excised preparation the facts are different. With ordi-nary use for two, or even three or four hours experimentation, themuscle lasts extremely well, giving at the end of that time almost * Sertoli: Archives italiennes de biologic, 1883, iii, pp. 78-94-2 Capparelli; Archives italiennes de biologie, 1882, ii, pp. 291-302,- Morgen ;Untersuchungen aus der physiologischen Institut der Universitat Halle (Bern-steins), 1890, ii, pp. 139-169; Meirowsky: Archiv fiir die gesammte Physiologi

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