File:ΔFosB vi.svg
Original file (SVG file, nominally 935 × 965 pixels, file size: 245 KB)
Captions
Captions
Summary[edit]
| Description |
Source File:ΔFosB.svg The finished, wikilink annotated version is currently located at en:Template:Psychostimulant addiction; a more detailed image caption is located there as well. This image shows the signal transduction that occurs in nucleus accumbens D1-type medium spiny neurons that gives rise to psychostimulant addiction. This signaling cascade occurs during chronic high-dose use of certain dopaminergic stimulants (e.g., phenethylamine, methamphetamine, amphetamine, etc.). Cocaine induces a slightly different signaling cascade than the one shown here. |
| Source | |
| Author |
|date=2022-10-28 |source=Own work |author=Joseph Mickel (Seppi333); Translator: Mongrangvebet (viwiki) |permission= |other versions=File:Annotated ΔFosB.svg screenshot.png - labeled version }}
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 04:05, 28 October 2022 | | 935 × 965 (245 KB) | Mongrangvebet (talk | contribs) | Uploaded own work with UploadWizard |
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Metadata
- Amphetamine
- Substance abuse
- Substance dependence
- Signaling cascades
- Transcription factor Creb
- Cyclic adenosine monophosphate
- N-methyl-D-aspartate receptors
- Glutamate receptors
- Dopaminergic synapse
- Nucleus accumbens
- Mesolimbic pathway
- Dopamine
- Protein kinase A
- Calmodulin-dependent protein kinase
- L-type calcium channels
- Transcription factor FosB
- Protein phosphatase-1 (PP-1)
- Ion channels
- Neurotransmitter receptor signaling
- Addictions
- Methylphenidate
- Diagrams of methamphetamine
- Calmodulin
- DRD1
- Dopamine pathway
- G-protein signaling
- Gene expression regulation
- C-fos
- Neuron models
- SVG substance abuse
- SVG psychiatry