File:Zebra fish Inhibition of the FGF pathway by SU5402 does not show any similarities to U0126-treated embryos.jpg
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| Description | Zebra fish. Inhibition of the FGF pathway by SU5402 does not show any similarities to U0126-treated embryos. A-C: Expression of the Fgf-pathway target gene sef is downregulated in SU5402 (C) but not in U0126-treated (B) embryos. D-I: Expression of the notochordal marker genes col2a1 (D-F) and shh (G-I) also show different defects in SU5402 and U0126-treated embryos. J-M: Expression of lox1 (J, K) and lox5b (L-M) is not decreased normally by U0126-treatment. N, O: copa mRNA persists and is not downregulated by U0126-treatment. |
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| Source | https://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-213X-8-42#Fig7 https://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-213X-8-42 Hawkins, T.A., Cavodeassi, F., Erdélyi, F. et al. The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish. BMC Dev Biol 8, 42 (2008). |
| Author | Hawkins, T.A., Cavodeassi, F., Erdélyi, F. et al. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 00:11, 25 April 2024 | | 1,927 × 3,071 (2.41 MB) | Rasbak (talk | contribs) | |
| 00:07, 25 April 2024 |  | 1,200 × 1,912 (972 KB) | Rasbak (talk | contribs) | {{Information |description=Zebra fish. Inhibition of the FGF pathway by SU5402 does not show any similarities to U0126-treated embryos. A-C: Expression of the Fgf-pathway target gene sef is downregulated in SU5402 (C) but not in U0126-treated (B) embryos. D-I: Expression of the notochordal marker genes col2a1 (D-F) and shh (G-I) also show different defects in SU5402 and U0126-treated embryos. J-M: Expression of lox1 (J, K) and lox5b (L-M) is not decreased normally by U0126-treatment. N, O: co... |
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