File:Wnt Signaling in Kidney Disease (Homo sapiens).svg

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English: This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin transcription. The complex of Nphp2 and Nphp3 seem to help facilitate the process by controlling the Wnt signaling. Bergmann, et al. (2008) showed that Nphp3 deficiency in Xenopus resulted to planar cell polarity defects.
Date 23:18, 15 August 2019
Source Published as WP4150, revision 94404, at https://www.wikipathways.org/index.php/Pathway:WP4150?oldid=94404
Author WikiPathways community
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Creative Commons CC-Zero This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication.
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Date/TimeThumbnailDimensionsUserComment
current01:31, 17 August 2019Thumbnail for version as of 01:31, 17 August 2019800 × 600 (74 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
01:29, 17 August 2019Thumbnail for version as of 01:29, 17 August 2019800 × 600 (73 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
01:22, 17 August 2019Thumbnail for version as of 01:22, 17 August 2019800 × 600 (73 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
01:20, 17 August 2019Thumbnail for version as of 01:20, 17 August 2019800 × 600 (73 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
01:18, 17 August 2019Thumbnail for version as of 01:18, 17 August 2019800 × 600 (73 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
01:15, 17 August 2019Thumbnail for version as of 01:15, 17 August 2019800 × 600 (73 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
01:10, 17 August 2019Thumbnail for version as of 01:10, 17 August 2019800 × 600 (74 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
00:42, 17 August 2019Thumbnail for version as of 00:42, 17 August 2019800 × 600 (73 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
00:18, 17 August 2019Thumbnail for version as of 00:18, 17 August 2019800 × 600 (74 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
00:02, 17 August 2019Thumbnail for version as of 00:02, 17 August 2019800 × 600 (94 KB)WikiPathwaysProject (talk | contribs){{Information |Description = {{en|1=This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin tr...
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