File:Transactions of the Southern Surgical and Gynecological Association (1910) (14768677395).jpg

Identifier: transactionsofso2319sout (find matches)
Title: Transactions of the Southern Surgical and Gynecological Association
Year: 1910 (1910s)
Authors: Southern Surgical and Gynecological Association (U.S.)
Subjects: Surgery Gynecology Surgery Genital Diseases, Female
Publisher: (S.l.) : The Association
Contributing Library: Yale University, Cushing/Whitney Medical Library
Digitizing Sponsor: The College of Physicians of Philadelphia and the National Endowment for the Humanities

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The periacinar connective tissue may be rare or denseand there may or may not be lymphocytes present. Acini with suchcharacteristics may be visible to the naked eye (Fig. 1, a). The innerrow of cells is apparently pushed toward the lumen by the developmentof the second or outer row. The cells of the outer row have differentcharacteristics from the inner row, in that they are round, have clearprotoplasm and sharply defined round nuclei. These round hyperplastic cells are the blasse Zellen ofthe German writers, and were first described by Borst andWohlseeker (Saar). Borst considered these cells specific car-cinoma changes. Saar, however, says they occur in benigntumors, and that he saw them in a cystadenoma. Kurnfound them in a fibro-adenoma, and in the breast of a child. These authorities are probably all correct. BlasseZellen occur in this series in fibro-adenomata, cystadeno-mata, and carcinoma, but this fact does not prevent themfrom being the cells out of which carcinoma develops.
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1 £ c3 2 & * ■§ U ^ c3 O, r-T 03 • So o qq .a I •J 11 o3 O ° If J•§11 •si- « M §1 g ° S3 ^ to g O 0) 02 § A S III 3 .S 0J O) 0 3 03 02 O 3 w h <~ m O 1 d £ s 2 ~ O bjo cu f - § o O ^ O +j 3 ~0) o3 ^=3o rt 2 ° bC to 03 & WM. CARPENTER MAC CARTY 265 Neither does it prohibit the same cells from being in stagesof hyperplasia in all three of these tumors, because it is wellknown that fibro-adenomata and cystadenomata developinto carcinoma, and, moreover, that cystadenomata andfibro-adenomata may be synonymous, depending upon theportion of the tumor examined. During hyperplasia of the epithelium and the formationof cysts from the acini the interacinar stroma not infre-quently becomes reduced in amount and completely disap-pears. This destruction allows the acini to fuse and formlarger cysts which, in their early development afterfusion, still have the remains of partially destroyed bridgesof interacinar stroma projecting into the lumen. They arecove

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