File:Transactions of the Pathological Society of Philadelphia (1890) (14771427962).jpg

Identifier: transactionsofpa1518path (find matches)
Title: Transactions of the Pathological Society of Philadelphia
Year: 1891 (1890s)
Authors: Pathological Society of Philadelphia (1857- )
Subjects: Pathological Society of Philadelphia (1857- ) Medicine Societies, Medical
Publisher: Philadelphia : Pathological Society of Philadelphia
Contributing Library: The College of Physicians of Philadelphia Historical Medical Library
Digitizing Sponsor: The College of Physicians of Philadelphia and the National Endowment for the Humanities

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e times the normalsize. It feels like a solid mass of flesh, as it in reality is. The ventriclesare small and the walls are thickened. The walls of the left ventricleare five-eighths of an inch thick, those of the right three-eighths of aninch thick. The valves are normal, but from the great thickness of theventricular walls one would suppose they were practically useless. Theright testicle is in the abdomen, the left is in the ring. There were noother abnormalities noted. The mother made a good recovery. Congenital cystic degeneration of the kidneys is a well-known lesionand has been the subject of numberless essays. Though the child isgenerally stillborn, or dies soon after birth, what is apparently the samecondition has been found in adults. 186 GENI TO -URINARY SYSTEM. Frequently the condition is connected with various other malforma-tions—hydrocephalus, malformed genitals, etc. The same mother has been known to give birth to children at differenttimes affected in the same wTay.
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In 1845, Virchow examined a case carefully and gave as his explana-tion that the original seat of the cyst-formation is in the uriniferoustubules or in the Malpighian capsule. During the progress of thedisease these cysts may lose their connection with the tubule fromwhich they started. He considers that the original occlusion is fre-quently due to infarcts of uric acid salts, though it may be due to aninflammation starting in the pyramids. He considers also, from the fact that the same woman may give birthto successive children with this abnormality, that the uric acid diathesis GEXITO-URIXARY SYSTEM. 187 in the mother may be the original cause of the trouble in the child.(Virchows Gesammelt Abhandlungen, p. 870.) Virchows explanation is accepted by most of the pathologists of to-day, though I think they repudiate the idea of the uric acid diathesisas a cause. The normal kidney substance is more or less destroyed inall cases, but in most there can be found here and there spots wherec

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