File:Transactions of the American Association of Obstetricians, Gynecologists, and Abdominal Surgeons for the year (1920) (14593293239).jpg

Identifier: transactionsofam3319amer (find matches)
Title: Transactions of the American Association of Obstetricians, Gynecologists, and Abdominal Surgeons for the year ...
Year: 1920 (1920s)
Authors: American Association of Obstetricians, Gynecologists, and Abdominal Surgeons
Subjects: Gynecology Obstetrics Gynecology Obstetrics
Publisher: St. Louis : C.V. Mosby
Contributing Library: Columbia University Libraries
Digitizing Sponsor: National Endowment for the Humanities (NEH)

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(b) After excision of the liver, the temperature of the brain falls pro-gressively until death (Fig. 2). (c) The brain-cells show changes in the cytologic structure whichare progressive from the moment the liver is excised (Fig. 3). (d) In every type of exhaustion from whatever cause, the cells of theliver show cytologic changes, such as diminished power of differentialstaining, edema, and increased electric conductivity (Fig. 4). (e) Granting adequate circulation and respiration in a decapitatedanimal, the excision of the liver causes death earlier than decapitation oradrenalectomy. From these findings we may suppose that the integrity of the liveris essential to the work of the brain, just as the integrity of the liver isessential to the elimination of the acid by-products of metabolism by thekidneys and the lungs. When the liver is excised, the blood tends to be- 6 GEORGE W. CRTLE
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Fig. 3.—Cytologic changes in the brain cells afternormal cerebellum of a dog. B ai.d D, section ofexcised. (A and B from photomicrographs x85. C ai excision of the liver. A and C, section ofcerebellum of a dog whose liver had beennd D from photomicrographs x3l0.) ADDRESS OF THE PRESIDENT 7 come acid as the animal approaches exhaustion. Neither the transfusionof blood nor the administration of adrenalin or of morphine exerts theleast check on the exhaustion and death which follow excision of theliver. For its oxidizing and reducing power, the liver apparently depends,in part at least, on the adrenals; for the excessive intravenous injectionof adrenalin on the one hand, and adrenalectomy on the other, causemarked cytologic changes in the liver cells—chromatolysis, edema, eccen-tric position of the nucleus. As noted above, in our electric conductivity studies we found thatin exhaustion from any cause the liver and the brain were affected inopposite directions, i.e., in extreme exhaus

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