File:The Journal of biological chemistry (1905) (14597400487).jpg

Identifier: journalofbiologi56ameruoft (find matches)
Title: The Journal of biological chemistry
Year: 1905 (1900s)
Authors: American Society for Biochemistry and Molecular Biology American Society of Biological Chemists Rockefeller Institute for Medical Research
Subjects: Biochemistry
Publisher: (Baltimore, etc.) American Society for Biochemistry and Molecular Biology (etc.)
Contributing Library: Internet Archive
Digitizing Sponsor: Internet Archive

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Fig. 4. the efficiency of the ventilation under it, a slight rise in alkalireserve being observed with vigorous ventilation by streaming airthrough the mask, and a slight fall when increased dead space,diminished oxygen tension, or increased CO2 tension are induced.The experiments with oxjgen are, however, not entirely con-sistent with the interpretation given above. The second inter-pretation is based upon the fact that if the variations in alkali Cullen, Austin, Kornblum, and Robinson 637
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638 Initial Acidosis in Anesthesia reserve in J-hese control experiments are plotted regardless of theparticular procedure adopted (see Fig. 6) it will be found thatthe changes distribute themselves in such a way that they mightbe interpreted as the fortuitous variations to be expected atrepeated bleedings. Whichever interpretation be preferred, wemay conclude that the control experiments indicate that the fac-tors taken into consideration do not produce at least individuallya change in alkali reserve greater than 5 mivi. Group III. (Experiments 6, 7, and 8; Fig. 7.) Nitrous Oxids Anesthesia.-—The effect of nitrous oxide whenadministered either pure or as 95 per cent nitrous oxide and 5per cent oxygen is shown in Experiments 6 and 7.In both these experiments it was found impossibleto secure anesthesia in the dog without using 95per cent or more of N2O. This inevitably led tomarked anoxemia. There occurred at first a risein total (CO2) in the serum associated in Experi-ment 6 with a

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