File:The Journal of biological chemistry (1905) (14597192970).jpg

Identifier: journalofbiologi56ameruoft (find matches)
Title: The Journal of biological chemistry
Year: 1905 (1900s)
Authors: American Society for Biochemistry and Molecular Biology American Society of Biological Chemists Rockefeller Institute for Medical Research
Subjects: Biochemistry
Publisher: (Baltimore, etc.) American Society for Biochemistry and Molecular Biology (etc.)
Contributing Library: Internet Archive
Digitizing Sponsor: Internet Archive

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fter having been reared on ourstandard stock ration. Each group represents four animals taken fromseparate litters of six. Groups 1719 and 1721 were started at an age of 22days, Group 1722 at 25 days. Of the twelve rats all developed ophthalmiasin from 6 to 8 weeks, average 7, after being put on the ration. Respiratoryinfections were not so evident, only two cases developing, in Rat 5758 at10 weeks and in Rat 5746 at S weeks after being put on the ration. The infec-tions were indicated by a hemorrhagic rhinitis. Death occurred in from8 to 11 weeks, average 10. in growth though the animals were all started at about the samesize and age with an average of 50 gm. at 24 days in Chart IIas compared with 56 gm. at 22 days for those shown in Chart III.The former averaged 88 gm. as the maximum weight, while thelatter averaged 176 gm. Maintenance of life varied in the samedirection, an average of 10 weeks in Chart II as compared with15 weeks for those shown in Chart III. Difference in the time
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Chart III. Shows the growth obtained in young rats when put on aration practically free from the fat-soluble vitamine after having beenreared on our standard stock ration which had been enriched in its fat-soluble vitamine content by the addition of 5 per cent of cod liver oil. Eachgroup represents separate litters, the first one containing only four individ-uals the second five, and the last two, six. They were started at approxi-mately the same age; Groups 1715 and 1716 at 22 daj^s, and Groups 1717 and1718 at 21 days. Of the sixteen rats only two, viz. Rats 5734 and 5742, did not develop anophthalmia, the others all developed it in from 11 to 17 weeks, average 13,after being put on the ration. One rat did not show any signs of respiratory disease, the others con-tracted it in from 13 to 19 weeks, average 14, after the feeding of the fat-soluble vitamine-free ration was begun. Death of the animals terminated the various feeding trials in from 13 to21 weeks, average 15 weeks. 335 336

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