File:The British journal of dermatology (1888) (14750262896).jpg

Identifier: britishjournalof32brit (find matches)
Title: The British journal of dermatology
Year: 1888 (1880s)
Authors: British Association of Dermatology
Subjects: Dermatology Syphilis
Publisher: London H.K. Lewis (etc.)
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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Fig. 2.—Shows the condition of the left leg in January. 1920. Activeulceration has begun again at the upper and inner part of the healed lesionshown in Fig. 1. The different zones desciibed in the text are clearlyshown. TO ILLUSTRATE DR. H, W. BARBERS AND MR. F. A. KNOTTS CASE OF RECURRENT ULCERATION OF THE SKIN CAUSED BY A DIPHTHEROID BACILLUS. A CASL; of KECrinjKXl ULCKUAIION (»!• TIIK SKIX. 75 I Sliortly afterwards a new lesion appeared at tlie inner side of theleft ankle (see Fig. o). On January oOtli a dose of 2^, millions of the vaccine was given,with little or no reaction. On Fel)rnary 4th a dose of 5 millions wasinjected and this was followed by some malaise, with increased painand swelling in the new lesion on the ankle. On February 12th adose of 10 millions was given. Twenty-four hours later a mostintense reaction took place. The patient became feverisli, his head
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Fig. 3.—Shows a reeeut lesion wliicli is lieginning to break down. Xotetlie criViriform appearance produced by the destruction of the overlyingepithelium. The raised oedematous spreading edge is also well seen.Scars of old lesions are shown aroimd the ankle. ached, he had shivering attacks and could not sleep. In both theactive lesions on tlie leg there ivas a very marked focal reaction: the-edges became acutely congested and oedematous, and the patient notonly felt great pain in these situations, but the healed area began tohum and became bright jnnh in colour. This focal reaction lasted foralmost forty-eight hours; the pain and oedema then disappeared. At the time of writing the upper of the two active lesions is healing■satisfactorily, whereas that on the ankle is still rather angry-looking.and painful. It is hoped that when these two lesions are completely 76 A CASE OF RECUERENT ULOERATION OF THE SKIN. healed a further outburst of the disease may be prevented by ajudicious use

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