File:TRPC5 Chemo.jpg
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DescriptionTRPC5 Chemo.jpg |
English: Two distinct TRPC5 mediated the cancer drug resistance. (a) TRPC5 overexpression activates the transcription factor NFATC3 Ca2+ signaling pathway, leading to p-gp overexpression. Moreover, the overexpressed p-gp expels chemotherapeutic drugs triggering chemoresistance. (b) Chemoresistant breast cancer cells overexpressing TRPC5 transfer channel units to chemo sensitive recipient cells via extracellular vesicles (EV), leading to the development of TRPC5-mediated chemoresistance in these cells. |
Date | |
Source | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536409/ |
Author | Mayar Soussi, Alice Hasselsweiller, and Dimitra Gkika |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 03:45, 3 February 2024 | 1,079 × 1,510 (293 KB) | PecMo (talk | contribs) | Uploaded a work by Mayar Soussi, Alice Hasselsweiller, and Dimitra Gkika from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536409/ with UploadWizard |
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Date and time of data generation | 05:28, 3 February 2024 |
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User comments | 1072 |
Width | 1,079 px |
Height | 1,510 px |
Orientation | Normal |
File change date and time | 05:28, 3 February 2024 |
DateTimeOriginal subseconds | 985 |
Light source | Unknown |
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3 February 2024
300,257 byte
1,510 pixel
1,079 pixel
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26917eb445ebcb3dc93a0b388f17d23f0ee86f32
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