File:TMB-Antigen Association.jpg
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Captions
Captions
TMB Association with the Number of Expressed Neoantigens on Tumour Cell Surface
Summary
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| Description |
English: Mutations (red marks) in segments of the genome are reflected in proteins produced from them through transcription and translation. Some proteins are fragmented into peptides that can then be presented as antigens on the surface of cell membranes by major histocompatibility complexes (MHCs). If presented antigens accumulate enough mutations, they can bind and activate T-cells which can then initiate immune mediated cell death. |
| Date | |
| Source | Own work |
| Author | Ryanrile |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 17:54, 3 March 2021 | | 720 × 504 (113 KB) | Ryanrile (talk | contribs) | Uploaded own work with UploadWizard |
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