File:Surgical bacteriology (1889) (14594424458).jpg

Identifier: surgicalbacterio00senn (find matches)
Title: Surgical bacteriology
Year: 1889 (1880s)
Authors: Senn, Nicholas, 1844-1908
Subjects: Pathology, Surgical Medical bacteriology Bacteriology General Surgery
Publisher: Philadelphia : Lea
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons and Harvard Medical School

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ined to be sceptical in regard to the etiological Iole playedby it. Koch produced artificial tuberculosis in over five hun-dred animals with material from different tubercular lesions andexamined them all with the greatest care. Of the bacillus heproduced forty-three pure cultures, some of which he continuedthrough over thirty generations, occupying a period of twoyears. We shall see that inoculations with material from so-called scrofulous glands produce the same effect as when lupustissue is used, and must, therefore, attribute their existence tothe same cause. Arloing (Comptes rendus, t. 99, p. 661) prepared an emulsionfrom a simple scrofulous gland, caseous in the centre, which wastaken from a boy aged fourteen. This was injected beneath theskin of ten rabbits, and the same number of guinea-pigs.Visceral tuberculosis developed in all guinea-pigs, but therabbits remained healthy, except that two showed yellowcaseous granulations at the seat of inoculation. From a gland PLATE V T T,
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Tubercular eruption in the iris of a rabbit, fifth day after inoculation.Zeiss ^^. (Baumgarten.) Beg. T. Formation of tubercles beginning (separation of whitecorpuscles). E. Endothelium of the anterior surface of the iris. Ep. Epithelium of the posterior surface of the iris. P. Iris parenchyma. Gf. Bloodvessels. TUBERCULOSIS. 163 removed later, from the same boy, a similar emulsion was madeand injected into the peritoneal cavity of six rabbits and sixguinea-pigs. As before, the guinea-pigs all presented tubercularlesions; the rabbits, on being killed, were found to be perfectlyhealthy. In two instances, pus from strumous abscesses gavesimilar results. Some glands excised from the neck of a youngwoman produced tuberculosis both in rabbits and in guinea-pigs,but the patient died three weeks after the operation from miliarytuberculosis. Arloing appears to consider this case as outsidethe general category of strumous glands. From these experi-ments he inferred that either scrofula and tub

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