File:Superficial spreading melanoma on dermoscopy, reflectance confocal microscopy and histopathology 2.jpg

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Superficial spreading melanoma on dermoscopy, reflectance confocal microscopy and histopathology

Summary

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Description
English: Superficial spreading melanoma on dermoscopy, reflectance confocal microscopy and histopathology: Breslow thickness 0,79 mm. This lesion shows on dermoscopy (A) pseudopods (white circle

corresponds to the punch area). RCM mosaic image (B, 363 mm) at the level of the DEJ shows compact aggregates of atypical cells distributed in a linear arrangement toward the periphery with a dense nest at the extremity (the area inside the dashed square is represented in figure C). RCM individual image (C, 0,560,5 mm) at the level of the DEJ shows a pseudopod in detail, characterized by elongated, dense and bright peripheral aggregate. Perpendicular section (D) shows nests of atypical melanocytes distributed contiguously toward the periphery along the DEJ. Transverse

section (E) shows nests of atypical cells arranged in a linear manner throughout the periphery of the lesion (black arrows).
Date
Source (2013). "Learning Reflectance Confocal Microscopy of Melanocytic Skin Lesions through Histopathologic Transversal Sections". PLoS ONE 8 (12): e81205. DOI:10.1371/journal.pone.0081205. ISSN 1932-6203.
-"This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited."
Author

Juliana Casagrande Tavoloni Braga, Mariana Petaccia Macedo, Clovis Pinto, João Duprat, Maria

Dirlei Begnami, Giovanni Pellacani, Gisele Gargantini Rezze

Licensing

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