File:Superficial spreading melanoma in situ on dermoscopy, reflectance confocal microscopy and histopathology 1.jpg
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[edit]DescriptionSuperficial spreading melanoma in situ on dermoscopy, reflectance confocal microscopy and histopathology 1.jpg |
English: Superficial spreading melanoma in situ on dermoscopy, reflectance confocal microscopy and histopathology: Superficial spreading melanoma in situ. This lesion shows on dermoscopy (A) a slightly pigmented network (white circle corresponds
to the punch area). RCM mosaic image (B, 161 mm) at the level of the DEJ shows irregular and dishomogeneous dermal papillae with dendritic cells (white arrows). RCM individual image (C, 0,560,5 mm) at the level of the DEJ shows dendritic cells forming ‘‘bridges’’ called mitochondria-like structures (white arrow). Perpendicular section (D) shows disarrangement of the rete ridge and the increased number of atypical melanocytes. Transverse section (E, HE staining) shows atypical melanocytes protruding into the dermal papillae forming bridges (black arrows). Transverse section (F, Melan-A staining) shows cells positive for Melan-A protruding into the dermal papillae (white arrows). |
Date | |
Source |
(2013). "Learning Reflectance Confocal Microscopy of Melanocytic Skin Lesions through Histopathologic Transversal Sections". PLoS ONE 8 (12): e81205. DOI:10.1371/journal.pone.0081205. ISSN 1932-6203. -"This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited." |
Author |
Juliana Casagrande Tavoloni Braga, Mariana Petaccia Macedo, Clovis Pinto, João Duprat, Maria Dirlei Begnami, Giovanni Pellacani, Gisele Gargantini Rezze |
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