File:Structural modeling of RshSTT200.webp
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From the study "A novel SARS-CoV-2 related coronavirus in bats from Cambodia"
Summary
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| Description |
English: "a Homology modeling of the RBD structure. The three-dimensional structure of the RshSTT200 Spike RBD was modeled using the Swiss-Model program employing the structure of SARS-CoV-2 (PDB: 6yla.1) as a template. The core and external subdomains are colored orange, and gray for RshSTT200 and SARS-CoV-2, respectively. The shortening a loop near the receptor-binding site of RshSTT200 are indicated by a black rectangle. The cysteines involved in a conserved disulfide bond are indicated. b Alignment of the receptor binding motif amino acid sequences of selected betaCoVs. c RshSTT200 spike (deleted for the last 21 amino acids) pseudovirus entry into HEK293T cells transfected with either RshACE2, hACE2 or an empty vector (pLenti-puro). d SARS-CoV-2 spike pseudovirus entry into HEK293T cells transfected with either RshACE2, hACE2 or an empty vector (pLenti-puro). Data are represented as mean ± standard deviation of technical replicates (n = 4) and are representative of three independent experiments. Source data are provided as a Source Data file." |
| Date | |
| Source | https://www.nature.com/articles/s41467-021-26809-4 |
| Author | Authors of the study: Deborah Delaune, Vibol Hul, Erik A. Karlsson, Alexandre Hassanin, Tey Putita Ou, Artem Baidaliuk, Fabiana Gámbaro, Matthieu Prot, Vuong Tan Tu, Sokha Chea, Lucy Keatts, Jonna Mazet, Christine K. Johnson, Philippe Buchy, Philippe Dussart, Tracey Goldstein, Etienne Simon-Lorière & Veasna Duong |
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 21:58, 13 December 2021 | | 1,999 × 973 (223 KB) | Prototyperspective (talk | contribs) | Uploaded a work by Authors of the study: Deborah Delaune, Vibol Hul, Erik A. Karlsson, Alexandre Hassanin, Tey Putita Ou, Artem Baidaliuk, Fabiana Gámbaro, Matthieu Prot, Vuong Tan Tu, Sokha Chea, Lucy Keatts, Jonna Mazet, Christine K. Johnson, Philippe Buchy, Philippe Dussart, Tracey Goldstein, Etienne Simon-Lorière & Veasna Duong from https://www.nature.com/articles/s41467-021-26809-4 with UploadWizard |
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