File:Skull of a male acromegaly patient (1904).jpg

Identifier: sajoussanalytica01sajouoft (find matches)
Title: Sajous's analytical cyclopædia of practical medicine
Year: 1904 (1900s)
Authors: Sajous, Charles Euchariste de Médicis, 1852-1929
Subjects: Medicine Medicine -- Practice
Publisher: Philadelphia : F.A. Davis Co.
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: MSN

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s, or after deathon the autopsy table, the existence of a view). (Dufrane and F. E. Launois.) from studies of the skeletons of giants.Langer reports having found an in-crease in the length, breadth, and depthof the sella turcica in every case, andit is well known that in pathologicalstates, as well as normally, the dimen-sions of this bony fossa in the sphe-noid are those best suited for its con-tents. The general conclusion warranted byall these mutually confirmatory data is 292 ACROMKGALY (LAUXOIS AXD CESBRON). that, whether associated zvith infantilismor acromegaly, yiyantism ahvays occursin association with a tumor of the hy-pophysis. This assertion cannot, ofcourse, be given as applying to all futureobservations, but in view of its uniform acromegaly with or without giantism.Tliat the relationship between acro-megaly and giantism is close isshown by the fact that a consider-able percentage of acromegalics aregiants and that a still larger percent-age of giants develop acromegaly.
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Skull of the giant Constantin (anterior view). (Dufrane and P. E. Launois.) confirmation by those of the past it is, at least, very impressive. Hyperactivity of the anterior lobeof the pituitary coming on before thecompletion of epiphyseal ossification,results in giantism, that is to say, theindividual is overgrown but wellproportioned. After epiphyseal ossi-fication is complete, however, hyper-activity of the hypophysis results in Symmers (Interstate Med. Jour.,Nov., 1917). COURSE AND DURATION.— Established acromegaly is generallyobserved in adults, male or female.The initial dystrophic phenomena ap-pear at the age of 18 to 25 years, i.e..at the period in which, under normalconditions, growth is continued and ACROMEGALY (LAUNOIS AND CESBRON). 293 completed. Sometimes it is headache isted, and under these conditions the which leads the std:)ject to consult a question arises in our minds whether physician. Other victims, frightened they could not have created a disturb- at seeing the

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