File:Schematic of epiboly progression.png

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Description Figure 1.Schematic of epiboly progression. Epiboly begins when the yolk (yellow) domes toward the animal pole (top), concomitant with radial intercalation of the deep cells of the blastoderm (green) to cover 30% of the embryo surface. At 30% epiboly, the yolk syncytial nuclei (YSN, dark- green circles) are maintained within the yolk syncytial layer (YSL) beneath the blastoderm and are associated with microtubules (black lines, surface view) that are oriented toward the vegetal pole within the very thin cortical, yolk cytoplasmic layer (YCL, light blue in cross-section). The enveloping layer (EVL, pink) forms a thin epithelial-like sheath on the surface of the deep cells and is connected to the YSL at the cell margin. The YCL cannot be distinguished from the yolk when viewed from the lateral surface. At 50% epiboly, the EVL and deep cells cover 50% of the embryo and lie more vegetally than the YSN, masking the YSN in the lateral surface view. An actin band (turquoise) forms in the YSL just vegetal to the margin at 50% epiboly and likely functions as a contractile mechanism to close the blastopore throughout the remainder of the epiboly process. By 75% epiboly, the YSN are located beneath the blastoderm, as well as vegetal to it (surface view). The blastopore is the exposed vegetal yolk, which continually decreases in circumference as epiboly progresses. doi:10.1371/journal.pgen.1000413.g001
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A Novel Role for MAPKAPK2 in Morphogenesis during Zebrafish Development. PLoS Genet 5(3): e1000413. doi:10.1371/journal.pgen.1000413

Editor: Gregory S. Barsh, Stanford University School of Medicine, United States of America
Author Holloway BA, Gomez de la Torre Canny S, Ye Y, Slusarski DC, Freisinger CM, et al.
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©2009 Holloway et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current10:01, 1 June 2024Thumbnail for version as of 10:01, 1 June 2024850 × 664 (354 KB)Rasbak (talk | contribs){{Information |description=Figure 1.Schematic of epiboly progression. Epiboly begins when the yolk (yellow) domes toward the animal pole (top), concomitant with radial intercalation of the deep cells of the blastoderm (green) to cover 30% of the embryo surface. At 30% epiboly, the yolk syncytial nuclei (YSN, dark- green circles) are maintained within the yolk syncytial layer (YSL) beneath the blastoderm and are associated with microtubules (black lines, surface view) that are oriented toward...

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