File:Sarcoidosis - Hamazaki-Wesenberg (H-W) bodies- Lymph node (6135441626).jpg
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[edit]DescriptionSarcoidosis - Hamazaki-Wesenberg (H-W) bodies- Lymph node (6135441626).jpg |
Although these structures may occasionally occur as inclusions within giant cells they are usually not encountered as inclusions but are found extracellulary in the sinusoids of granuloma-containing lymph nodes in sarcoidosis as well as in non-granulomatous lymph nodes from individuals with sarcoidosis and other conditions. H-W bodies are oval or spindle-shaped, range up to several microns in size, and appear yellow-brown with H&E stain . The pigment appears to be lipofuscin. Ultrastructural studies have shown that H-W bodies are giant lysosomes and residual bodies. They are acid-fast and stain with silver stains as well as a variety of other stains.When visualized with silver stains H-W bodies can be easily mistaken for budding yeasts due to clustering of individual bodies. H&E stain - oil immersion. |
Date | |
Source |
Sarcoidosis - Hamazaki-Wesenberg (H-W) bodies- Lymph node
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Author | Yale Rosen from USA |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 09:00, 12 February 2014 | 2,784 × 1,901 (2 MB) | File Upload Bot (Magnus Manske) (talk | contribs) | Transferred from Flickr by User:CFCF |
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Orientation | Normal |
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Software used | ACD Systems Digital Imaging |
File change date and time | 10:59, 4 August 2011 |
Y and C positioning | Centered |
DateTime subseconds | 9 |