File:Sanctuary of Asclepius at Epidaurus - Northeast Baths or Akoai.jpg

English: Ritual bathing formed a large part of the healing offered at Asclepiean sanctuaries. Pilgrims were required to bath before approaching the temple, and various bathing practices were recommended as cures. Several full-body bathing establishments were built at Epidaurus. The Northeast Baths were built at the beginning of the 3rd century AD. They may have been sponsored by the wealthy Roman senator, Antoninus, or been part of the extensive building program initiated by Caracalla. They were constructed using the technique known as opus mixtum which uses a combination of Roman rubble masonry and brickwork. No material from the baths appears to have been re-used from elsewhere as was common in other Roman period modifications. Towards the end of the 4th century, the north-western latrine was added, and the main bathing rooms were re-configured with several doorways blocked, new passageways built, and the baths extended with new rooms to the south-west. The entire complex covers an area of 650 square metres and is arranged in four parallel wings.

Entrance into the baths was from the west along a wide corridor which led to a plunge bath within an apse. Baths with this entrance design are not typical, although they are similar to the baths near the Olympieion in Athens. To the south of the entrance corridor were four cold bathing rooms decorated with a colonnade of Ionic columns. To the north, three warm baths spanned one wing. A further three hot baths and a sudatorium (sweat room) were located in the most northerly wing. A hypocaust heating system warmed each of the rooms to the north of the corridor. The Northeast Baths are the best preserved of the bathing complexes at Epidaurus. The walls remain standing to several metres in height. Visitors can clearly see the method of wall construction. This includes layers of semi-coursed rubble bonded with cement and coursed brickwork, as well as walls constructed with only the lower levels in worked stone blocks and the upper courses unusually built of solid brick. Mosaic pavements are preserved in the hallway and cold baths, including sections of marble lining to the lower walls. Wall niches to display statues, column fragments, ceramic pipes and hypocaust fragments can also be seen. In the frigidarium, part of the curve of the domed roof can be seen.

Located a short distance to the northeast, the Late Antique Baths were built during the late 4th or early 5th century. These baths continued to be used into the Christian period. These remain in a highly ruinous state along with associated underground aqueducts.