File:Rnai phenotype.png

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Description Early Examples of Gene Silencing in Transgenic Plants. TGS: Normally when two plants harboring separate transgenes encoding resistance to kanamycin (kan) or hygromycin (hyg), respectively, are crossed, 50% of the progeny are resistant to the individual antibiotics and 25% are resistant to a combination of both (top). In cases of silencing, expression of the KAN marker is extinguished in the presence of the HYG marker, as indicated by only 25% kan resistance and no double resistance (middle). PTGS: Transformation of wild-type Petunia (bottom left) with a transgene encoding a pigment protein can lead to loss of pigment (white areas) owing to cosuppression of the transgene and homologous endogenous plant gene.
Date Published: May 11, 2004
Source Matzke MA, Matzke AJM (2004) Planting the Seeds of a New Paradigm. PLoS Biol 2(5): e133 doi:10.1371/journal.pbio.0020133
Author Marjori A. Matzke, Antonius J. M. Matzke; credit Jan Kooter for the left and middle images, and Natalie Doetsch and Rich Jorgensen for the right images
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Other versions Petunias cropped: Image:Rnai phenotype petunia crop.png

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current02:01, 9 February 2007Thumbnail for version as of 02:01, 9 February 20071,363 × 1,258 (1.82 MB)Opabinia regalis (talk | contribs){{Information |Description=RNA-mediated silencing. |Source=Matzke MA, Matzke AJM (2004) Planting the Seeds of a New Paradigm. PLoS Biol 2(5): e133 http://dx.doi.org/10.1371/journal.pbio.0020133 |Date=Published: May 11, 2004 |Author=Marjori A. Matzke, Anto

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