File:Reprogramming the immune system using ES cells..jpg
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DescriptionReprogramming the immune system using ES cells..jpg |
English: A One goal would be the regeneration of thymic epithelium by direct differentiation of ES cells into cortical and medullary thymic progenitors which express graft antigens through the action of autoimmune regulator (AIRE) for re-educating the adult immune system. B Another goal would be to aim for “Hematopoietic mixed chimerism” using a mixture of both donor ES cell-derived and recipient hematopoietic stem cells (HSC) which then generate thymic dendritic cells (DC) capable of clonal deletion of donor- and auto-reactive T cells. |
Date | NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. |
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[1] Direct
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Author | Lui, K.O., Fairchild, P.J., and Waldmann, H., Prospects for ensuring acceptance of ES cell-derived tissues (September 30, 2010), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.54.1, http://www.stembook.org. |
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This file is licensed under the Creative Commons Attribution 3.0 Unported license.
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current | 18:03, 5 April 2013 | 360 × 492 (61 KB) | Smallbot (talk | contribs) | Uploading CC-BY images from the the StemBook http://www.stembook.org/ 1/173 |
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