File:Radium, X rays and the living cell (1915) (14768385282).jpg

Identifier: radiumxrayslivin00colwrich (find matches)
Title: Radium, X rays and the living cell
Year: 1915 (1910s)
Authors: Colwell, Hector Alfred Russ, Sidney
Subjects: X-rays -- Physiological effect
Publisher: London, G. Bell and sons
Contributing Library: University of California Libraries
Digitizing Sponsor: MSN

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^specific one. The changes in the blood-producing organs were the earliestrecognisable, and were found to fall into two groups : changes inthe lymphoid tissue of the spleen, lymph glands, and intestinalfollicles ; and changes in the bone-marrow and spleen pulp.The former appear within a few hours (2^-3) of irradiation, and
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Fig. 31.—Guinea-pig exposed to X rays for 5 hours, then killed. Section through spleen follicle. In the centre of the follicle large quantities of freenuclear fragments and numerous phagocytes. Mitteilung aus den Grenzgebieten der Medizin ti. Cliirurgie (14), 1905. are complete in about 24-36 hours ; the latter are only recognis-able after the lapse of a few days, and increase in intensity tillthe death of the animal occurs. The first effect of the radiation is the destmction of lymphoidtissue in every region of the body ; this process appears to bequite independent of the subsequent cell destruction that occursin the spleen pulp and bone-marrow. The rapidity with which the changes in the lymphoid tissueoccur render it most probable that the effect is indeed a directone, and that this particular kind of cell is among the most SPLEEN 20T vulnerable to the X rays. Heineke was of the opinion that theywere of all cells the most vulnerable ; but it is a question whetherthis might not be

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